5 Common Causes of Kidney Disease

Your kidneys are responsible for cleaning your blood, helping control blood pressure, making red blood cells, and more. When your kidneys are damaged, waste products and fluids can build up in your body. Various health conditions can affect the functions of the kidneys and may eventually lead to them failing if left untreated. Here are 5 common causes of kidney disease.


In the U.S., diabetic kidney disease is the number one cause of kidney failure. Chronically high levels of glucose in the blood can damage the filters and blood vessels in the kidneys.

High Blood Pressure

High blood pressure can damage blood vessels in the kidneys, and they may not work as well to remove wastes and extra fluid from your body. The excess fluid in the blood vessels may raise blood pressure even more, creating a dangerous cycle. High blood pressure is the second leading cause of kidney failure in the U.S.


Glomerulonephritis occurs when the chronic inflammation of the tiny filters in the kidneys damages them. It can happen on its own or as a part of another disease.

Polycystic Kidney Disease

This is a genetic condition that causes fluid-filled sacs to form in your kidneys. Over time, these can interfere with your kidney’s ability to function.

Kidney Obstructions

Kidney obstructions (obstructive uropathy) can occur due to a variety of factors. Blockage or compression of your ureter or urethra, through which urine exits your body may be the result of:

  • Injuries such as a pelvic fracture
  • Tumor masses that spread to your kidneys, bladder, uterus, or colon
  • Diseases of the digestive tract
  • Kidney stones trapped in your ureter
  • Blood clots
Feeling isolates due to kidney disease

Have you been diagnosed with kidney disease? If so, clinical research studies may help. Clinical Pharmacology of Miami is currently seeking individuals with kidney disease to join upcoming studies looking into potential new treatment options. To learn more, call (305) 817-2900, or visit our website for additional details.